The Panel

 

 

 

 

Graham Carter

GRAHAM CARTER

DEQAS Organiser

Graham started his professional career as a medical laboratory technician in a District General Hospital. After obtaining an MSc in clinical biochemistry at the University of Surrey (1972) he moved to London's Charing Cross Hospital as a Senior Biochemist. He was appointed Consultant Clinical Scientist in 1991 and remained in this post until his retirement from full time employment in September 2000. He was appointed an Honorary Senior Research Fellow of Imperial College, London in 2001.

Graham?s interest in vitamin D was stimulated by a visit to Dr. Richard Gray's laboratory at The Medical College of Wisconsin in the mid -1970's. The vitamin D EQAS was started in 1989 after two regional surveys revealed serious shortcomings in the performance of 25 hydroxyvitamin D assays. He was a member of the Advisory Panel for the Randox International Quality Assessment Scheme (RIQAS) from 1996 - 2002.

Jacqueline Berry

 

JACQUELINE BERRY

Jackie is a Senior Research Fellow in the Vitamin D Research Laboratories at the University of Manchester. She started her career as a Pharmacologist gaining a BSc from Leeds University (1972), followed by an MSc (1974) and PhD (1977) from the University of Manchester. Following a short period in the Department of Surgery she moved to the Department of Medicine to work with Professor Barbara Mawer in 1979. This started a lifelong interest in metabolic bone disease with a particular focus on vitamin D and assay methodology. In the early 1980s she helped develop an improved assay for measurement of 1,25-dihydroxyvitamin D (1,25D) using a monoclonal antibody, and this in-house assay is still in use today. Since 1994 she has been Deputy Director of the only Supraregional Assay Service in England and Wales for the combined assay of 25-hydroxyvitamin D with 1,25D, for which she gained ISO 9001:2000 and ISO 13485:2003 accreditation. Current research sponsored by Cancer Research UK and Food Standards Agency examines the relative contributions of diet and UV exposure to vitamin D "sufficiency" in the British population. She is a committee member of the British Bone Research Society.

Elaine Gunter

 

ELAINE GUNTER

Elaine Gunter B.S., MT(ASCP) was chief of the NHANES Laboratory (Centres for Disease Control and Prevention) from 1978-2001. This world-class nutritional biochemistry laboratory, specializes in assays for vitamins, trace elements, and nutritional anemias, and was founded in 1971 as the central laboratory for the National Health and Nutrition Examination Survey of the United States. Data from NHANES provided the first national normative estimates of vitamin D status in the U.S. population. Elaine's laboratory also provided the vitamin D analyses for the NCI-funded Navy Colon Adenoma Study, which demonstrated the efficacy of vitamin D supplementation in prevention of colon cancer, and a number of other related vitamin D studies.

Elaine founded and served as the first president of ISBER, the International Society for Biological and Environmental Repositories. From 2001-2005, she was Deputy Director for Management and Operations of the Division of Laboratory Sciences (the chemistry side of CDC), responsible for ensuring the successful management of all the personnel, facilities, procurement, contractual grants, and operational processes for a staff of 300 scientists. She is now an independent consultant in specimen banking and laboratory activities, and continues to make scientific contributions in those fields.

Glen Jones

 

GLENVILLE JONES

Glen received BSc and PhD degrees in biochemistry from Liverpool University before completing his postdoctoral training at the University of Calgary and University of Wisconsin-Madison. After holding Assistant/Associate Professor positions at the Research Institute, Hospital for Sick Children/University of Toronto (1975-84), Glen joined Queen's University, Kingston, Ontario, and is currently a full Professor in the Departments of Biochemistry and Medicine (1988-present). He was involved in the early design and application of clinical assays for vitamin D metabolites in patients with disorders of calcium homeostasis.

His research has helped to define the cytochrome-mediated mechanism by which 1a, 25- (OH)2D3 is destroyed after it has performed its action in the body. Current interests include study of the cytochromes involved in the action and clearance of vitamin D analogs, new drugs in the treatment of psoriasis, osteoporosis and cancer. Glen has been an associate editor of the American J Bone & Mineral Research as well as being grant reviewer for the MRC of Canada (1986-1996) and NIH/NCI in USA.

 

 

HUGH MAKIN

Hugh obtained his PhD at the institute of Child Health, University of London in 1966 and was awarded the degree DSc in 1996 for his research on steroid analysis. He has been successively Lecturer, Senior Lecturer and Professor in the Department of Clinical Biochemistry at St. Bartholomew's & the Royal London School of Medicine & Dentistry since joining the Medical School in 1967. His research interests involve the use of GC-MS for the measurement of vitamin D metabolites and, in collaboration with Glen Jones, the use of mass spectrometry for the identification of calcitriol analogue metabolites both in vivo and in vitro. Hugh was the Programme Adviser to the UK Food Standards Agency Phytoestrogen Research Programme which supported a phytoestrogen quality assurance scheme organised by the Institute of Food Research in Norwich.

 

 

KAREN PHINNEY

Karen is a group leader in the Biomolecular Measurement Division of the National Institute of Standards and Technology (NIST). She received her Ph.D. in analytical chemistry from the University of Hawaii - Manoa and joined NIST in 1994 as a postdoctoral research associate. Her expertise is in chromatographic separations and mass spectrometry and their application to quantitative measurements. Her work has included the development of analytical methods for vitamins and other analytes in dietary supplements, and she has coordinated the development of serum-based Standard Reference Materials (SRMs) for nutritional biomarkers, including vitamin D metabolites.

 

 

CHRIS SEMPOS

Chris received his Ph.D. in Nutritional Sciences from the University of Wisconsin-Madison in 1982. At the same time he earned an M.S. in Preventive Medicine-Epidemiology. He has had a long career in the US government working with both NIH and CDC. He joined the Office of Dietary Supplements (ODS) at NIH in July 2008, as Program Director for the ODS Population Studies Program. In addition, between 1999 and 2004 he was Professor of Epidemiology and Director of Graduate Studies in the Department of Social and Preventive Medicine, University of Buffalo, Buffalo, New York.

His research areas include nutritional epidemiology, public health surveillance methods, and biostatistics. He is a co-author of the textbook, Statistical Methods in Epidemiology. With his experience in nutrition, epidemiology and biostatistics he has spent much of his career being something of an intermediary among those disciplines.

As a graduate student at the University of Wisconsin he developed a life-long interest in vitamin D. When he joined ODS he was invited by the late Dr. Mary Frances Picciano to work with her on vitamin D and public health surveillance. As a result of that collaboration the international Vitamin D Standardization Program (VDSP) was developed in 2010. Chris is the coordinator for the VDSP.

 

 

RAMON DURAZO-ARVISU

Ramon is Professor of Public Health Sciences in the Department of Public Health Sciences at Loyola University Medical Center where he serves as the head of the Biostatistics Division and co-director of the Master's Program in Clinical Research Methods. He has a strong background in mathematics and computer intensive statistical methods. He received his Ph.D. from the University of Arizona in Applied Mathematics, where he spent three years teaching mathematics and statistics courses.

Ramon is an active member of the American Statistical Association. In 2000, he served as the program chair for the section in Epidemiology. He has organized sessions on Minority and Health and Diversity and the Risk of Cardiovascular Disease for the Association annual meetings and been appointed to the Committee of Minorities in Statistics (2003-2005, 2005-2008). He is also a member of the Eastern North American Region (ENAR) of the International Biometry Society for whom he moderated a workshop to discuss issues related to minority graduate students in Biostatistics. He is a member of the Society for the Advancement of Chicanos and Native Americans in Science (SACNAS). He was a member of the IOM Committee to Review Dietary Reference Intakes for Vitamin D and Calcium in North America.

 

 

PAT TWOMEY

Patrick Twomey is consultant chemical pathologist in St. Vincent's University Hospital, Dublin, the Laboratory Director for Clinical Chemistry within the St Vincent's Hospital Group and Associate Clinical Professor in the School of Medicine, University College Dublin. He obtained an Intercalated BSc in Biochemistry from University College Cork before being awarded his Medical degree. He is a Fellow of both the Faculty of Pathology at the Royal College of Physicians of Ireland and of the Royal College of Pathologists where he also is an examiner. He is the Acting Chair of the Joint Working Group on Quality Assessment in Pathology and past Chair of the Chemical Pathology National Quality Assurance Advisory Panel within the Royal College of Pathologists. He is Vice Dean of the Faculty of Pathology, Royal College of Physicians of Ireland and Treasurer of the Association of Clinical Pathologists. He has co-authored one text book, several book chapters and over 80 original publications in the fields of clinical biochemistry, metabolic medicine, lipids and nutrition. He is a member of the editorial boards of the Journal of Clinical Pathology and of the British Medical Journal Case Reports.